CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8818
Family Name Microsomal triglyceride transfer protein large subunit inhibitor 9-[4-[2-oxo-5-[(2-pyridin-2-ylbenzoyl)amino]-1,3,2$l^{5}-dioxaphosphinan-2-yl]butyl]-N-(2,2,2-trifluoroethyl)fluorene-9-carboxamide family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00390794 Functional Category Bioactive
Superfamily Microsomal triglyceride transfer protein large subunit Binder Superfamily
Class Class 1006

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Survival motor neuron protein and Beta-lactamase inhibitor CHE... 1 0
Substance-P receptor and Neuromedin-K receptor ligand 2-[3,5-b... 7 0
Microsomal triglyceride transfer protein large subunit inhibit... 4 0


External ID

Functional Category

Molecule Name

CFAMM00390794 CHEMBL184221 Bioactive 9-[4-[2-oxo-5-[(2-pyridin-2-ylbenzoyl)amino]-1,3,2$l^{5}-dioxaphosphinan-2-yl]butyl]-N-(2,2,2-trifluoroethyl)fluorene-9-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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