CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8821
Family Name Beta-3 adrenergic receptor and Beta-2 adrenergic receptor ligand [3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-(thiophen-2-ylsulfonylamino)phenyl]ethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate family
No. of Seeds 16 No. of Other Members 2
Family Centroid CFAMM00387838 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily
Class Class 3059

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Platelet-derived growth factor receptor alpha and Platelet-der... 6 8
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 26 47
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 9 22
Beta-3 adrenergic receptor ligand 4,5-dichloro-N-[3-[(1R)-1-hy... 4 3
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 0
Beta-3 adrenergic receptor ligand 2-amino-N-[3-[(1R)-1-hydroxy... 7 0
RAC-alpha serine/threonine-protein kinase inhibitor N-[(2S)-1-... 2 1
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 1 0
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
Beta-3 adrenergic receptor ligand 3-[2-[[(2R)-2-(3-chloropheny... 1 1


External ID

Functional Category

Molecule Name

CFAMM00390808 CHEMBL186059 Bioactive N-[3-[(1R)-1-hydroxy-2-[2-(7-phenylmethoxy-1H-indol-3-yl)ethylamino]ethyl]phenyl]thiophene-2-sulfonamide
CFAMM00390807 CHEMBL186196 Bioactive N-[3-[(1R)-2-[[(2R)-1-(7-ethoxy-1H-indol-3-yl)propan-2-yl]amino]-1-hydroxyethyl]phenyl]thiophene-2-sulfonamide
CFAMM00390806 CHEMBL185703 Bioactive 2-[[3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-(thiophen-2-ylsulfonylamino)phenyl]ethyl]amino]propyl]-1H-indol-7-yl]oxy]-N,N-dimethylacetamide
CFAMM00390810 CHEMBL188196 Bioactive 2-[[3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-(thiophen-2-ylsulfonylamino)phenyl]ethyl]amino]propyl]-1H-indol-7-yl]oxy]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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