CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8823
Family Name Melanocortin receptor 5 and Melanocyte-stimulating hormone receptor ligand 4-[[N-cyclohexyl-C-[(2R,5S)-2,5-dimethylpiperazin-1-yl]carbonimidoyl]amino]-N-[2-(2,4-dichlorophenyl)ethyl]benzamide family
No. of Seeds 3 No. of Other Members 23
Family Centroid CFAMM00390814 Functional Category Bioactive
Superfamily Huntingtin and Prelamin-A/C Binder Superfamily 35
Class Class 3113

Cousin Family NamesSeedsMembers
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 6
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
C-X-C chemokine receptor type 3 ligand AGN-PC-00PW0E family 3 11
P2X purinoceptor 7 inhibitor 2-(4-chlorophenyl)-N-[1-[(Z)-[(cy... 1 0


External ID

Functional Category

Molecule Name

CFAMM00390829 CHEMBL366042 Bioactive 4-[[N'-(2-amino-2-methylpropyl)-N-cyclohexylcarbamimidoyl]amino]-N-[2-(2,4-dichlorophenyl)ethyl]benzamide
CFAMM00390814 CHEMBL184432 Bioactive 4-[[N-cyclohexyl-C-[(2R,5S)-2,5-dimethylpiperazin-1-yl]carbonimidoyl]amino]-N-[2-(2,4-dichlorophenyl)ethyl]benzamide
CFAMM00390827 CHEMBL185469 Bioactive 4-[[N-cyclohexyl-C-[(3R)-3-methylpiperazin-1-yl]carbonimidoyl]amino]-N-[2-(2,4-dichlorophenyl)ethyl]benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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