CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8826
Family Name Mu-type opioid receptor ligand AGN-PC-075GAC family
No. of Seeds 16 No. of Other Members 8
Family Centroid CFAMM00390858 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 2495

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 23
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand A-317920 Family 9 240
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 4 18
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Fatty-acid amide hydrolase 1 Inhibitor Furan-2-ylmethylcarbami... 1 105
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 35
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Mu-type opioid receptor ligand AGN-PC-075GFE family 1 0
Mu-type opioid receptor ligand AGN-PC-075GG7 family 4 2
Mu-type opioid receptor ligand AGN-PC-075GAW family 2 1
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
Melanocortin receptor 4 ligand [(3R,4S)-4-(4-chlorophenyl)-1-p... 5 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 1
Mitogen-activated protein kinase 14 and Heat shock protein bet... 2 1


External ID

Functional Category

Molecule Name

CFAMM00390856 CHEMBL185668 Bioactive AGN-PC-075GGT
CFAMM00390862 CHEMBL363265 Bioactive AGN-PC-075GDE
CFAMM00390875 CHEMBL184744 Bioactive AGN-PC-075GF4
CFAMM00390861 CHEMBL185906 Bioactive AGN-PC-009TZH
CFAMM00390866 CHEMBL185980 Bioactive 4-[bromo-[(1R,5S)-8-(furan-3-ylmethyl)-8-azabicyclo[3.2.1]octan-3-ylidene]methyl]-N-ethylbenzamide
CFAMM00390880 CHEMBL185229 Bioactive AGN-PC-075GCF
CFAMM00390873 CHEMBL187376 Bioactive AGN-PC-075GDH
CFAMM00390860 CHEMBL264290 Bioactive AGN-PC-075GDS
CFAMM00390879 CHEMBL184453 Bioactive AGN-PC-075GCQ
CFAMM00390872 CHEMBL186742 Bioactive AGN-PC-075GAB
CFAMM00390878 CHEMBL186505 Bioactive 4-[cyano-[(1R,5S)-8-(furan-3-ylmethyl)-8-azabicyclo[3.2.1]octan-3-ylidene]methyl]-N-ethylbenzamide
CFAMM00390871 CHEMBL365885 Bioactive AGN-PC-075GAG
CFAMM00390858 CHEMBL365068 Bioactive AGN-PC-075GAC
CFAMM00390877 CHEMBL434903 Bioactive AGN-PC-075GDK
CFAMM00390870 CHEMBL363015 Bioactive AGN-PC-075GBL
CFAMM00390857 CHEMBL363287 Bioactive AGN-PC-075GEQ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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