CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8828
Family Name Retinoic acid receptor RXR-alpha ligand 6-[(3-butoxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-cyclopropylidenemethyl]pyridine-3-carboxylic acid family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00390891 Functional Category Bioactive
Superfamily Menin and Prelamin-A/C Binder Superfamily 14
Class Class 2009

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
RAF proto-oncogene serine/threonine-protein kinase Inhibitor 5... 3 7
Renin Inhibitor CP-305202 Family 9 30
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Leukotriene B4 receptor 1 ligand AGN-PC-04XM3V family 3 10
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Cellular tumor antigen p53 and Lethal(3)malignant brain tumor-... 1 6
Prostaglandin D2 receptor 2 ligand SureCN137822 family 3 0
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Proteinase-activated receptor 1 ligand (3R,3aR,4S,5R,6S,7aS)-5... 2 3
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 5
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Thromboxane-A synthase inhibitor SureCN9045578 family 1 12
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390891 CHEMBL184497 Bioactive 6-[(3-butoxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-cyclopropylidenemethyl]pyridine-3-carboxylic acid
CFAMM00390893 CHEMBL366112 Bioactive AGN-PC-006VG6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26824 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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