CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8829
Family Name Glucocorticoid receptor ligand [(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(3-methoxyphenyl)methanol family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00390898 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Carbonic anhydrase 9 Binder Superfamily
Class Class 4640

Cousin Family NamesSeedsMembers
PF-02545920 family 16 140
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Glucocorticoid receptor Ligand 1-(3-chloro-4-fluorophenyl)-2,2... 1 13
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 10
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 6
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00CFYH ... 2 1
Glucocorticoid receptor ligand [(4aR,5S)-1-(4-fluorophenyl)-4a... 27 33
Glucocorticoid receptor ligand SureCN12956559 family 11 0
Glucocorticoid receptor ligand SureCN13477113 family 19 3


External ID

Functional Category

Molecule Name

CFAMM00390896 CHEMBL313400 Bioactive SureCN12956541
CFAMM00390894 CHEMBL184578 Bioactive 3-[[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-hydroxymethyl]phenol
CFAMM00390900 CHEMBL81397 Bioactive SureCN12956251
CFAMM00390899 CHEMBL79378 Bioactive SureCN13581474
CFAMM00390898 CHEMBL366093 Bioactive [(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(3-methoxyphenyl)methanol
CFAMM00390897 CHEMBL186930 Bioactive 4-[[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-hydroxymethyl]phenol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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