CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8832
Family Name Platelet-derived growth factor receptor beta ligand AGN-PC-075FQH family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00390924 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin transporter Binder Superfamily 5
Class Class 938

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 67 130
Tivozanib family 4 6
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Dual specificity mitogen-activated protein kinase kinase 1 inh... 10 54
Dual specificity mitogen-activated protein kinase kinase 1 inh... 5 7
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 1 15
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 19 11
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 8 12
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Equilibrative nucleoside transporter 1 inhibitor SureCN9046933... 2 9
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS5MA ... 3 4
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS94Q ... 6 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Receptor tyrosine-protein kinase erbB-2 and Tyrosine-protein k... 1 0
Aurora kinase A inhibitor AGN-PC-0760BB family 1 1
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Transient receptor potential cation channel subfamily V member... 2 4
Hepatocyte growth factor receptor ligand 1-[(E)-(2,4-difluorop... 2 0
Hepatocyte growth factor receptor ligand 6-[(1S)-1-[6-(2,3-dih... 1 5
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 7
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390924 CHEMBL184642 Bioactive AGN-PC-075FQH
CFAMM00390923 CHEMBL364601 Bioactive AGN-PC-075FQI
CFAMM00390922 CHEMBL186719 Bioactive AGN-PC-075FRN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543