CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Renin inhibitor AGN-PC-07ZC01 family
No. of Seeds 12 No. of Other Members 16
Family Centroid CFAMM00316819 Functional Category Bioactive
Superfamily Renin and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 3124

Cousin Family NamesSeedsMembers
Renin inhibitor (1S,5S)-7-[4-[3-(2-chloro-3,6-difluorophenoxy)... 11 16
Renin inhibitor (1R,5R)-3-[4-[3-(2-chloro-3,6-difluorophenoxy)... 5 2
Renin inhibitor SureCN1472318 family 4 1
Renin inhibitor AGN-PC-04XLXA family 9 5
Renin inhibitor AGN-PC-04XM0H family 3 0
Renin and Cytochrome P450 3A4 inhibitor (3R,4S)-N-[[2-chloro-5... 28 3
Renin and Potassium voltage-gated channel subfamily H member 2... 17 2
Renin and Cytochrome P450 3A4 inhibitor (3S,4R)-N-cyclopropyl-... 4 10
Renin inhibitor (1R,5S)-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2... 9 0
Renin inhibitor (1R,5S)-3-acetyl-N-cyclopropyl-N-[(2,3-dichlor... 11 0
Renin inhibitor SureCN5073976 family 6 0
Renin inhibitor 3-(4-amino-4-oxobutanoyl)-N-[(2-chlorophenyl)m... 2 0
Renin inhibitor (1R,5S)-3-acetyl-7-[4-[3-(2-bromo-5-fluorophen... 3 0


External ID

Functional Category

Molecule Name

CFAMM00316828 CHEMBL1092525 Bioactive AGN-PC-07ZC18
CFAMM00316821 CHEMBL1093289 Bioactive AGN-PC-07ZC05
CFAMM00316820 CHEMBL1093287 Bioactive AGN-PC-07ZC02
CFAMM00316819 CHEMBL1093285 Bioactive AGN-PC-07ZC01
CFAMM00316818 CHEMBL1093934 Bioactive (2S)-2-(aminomethyl)-N-[[2-chloro-5-(3-cyanopropyl)phenyl]methyl]-N-cyclopropyl-3-[4-[3-(2,6-dichloro-4-methylphenoxy)propyl]phenyl]propanamide
CFAMM00316817 CHEMBL1092186 Bioactive AGN-PC-00QPXT
CFAMM00316830 CHEMBL1093290 Bioactive AGN-PC-07ZC06
CFAMM00316816 CHEMBL1092187 Bioactive AGN-PC-07ZC03
CFAMM00316829 CHEMBL1092524 Bioactive AGN-PC-07ZC16
CFAMM00316822 CHEMBL1093288 Bioactive AGN-PC-07ZC04

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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