CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8854
Family Name Transient receptor potential cation channel subfamily V member 1 ligand (2R)-N-(4-tert-butylphenyl)-4-(6-chloro-4-methylpyridazin-3-yl)-2-methylpiperazine-1-carboxamide family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00391033 Functional Category Bioactive
Superfamily Lysosomal alpha-glucosidase and Microtubule-associated protein tau Binder Superfamily
Class Class 1502

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Transient receptor potential cation channel subfamily V member... 16 295
Reverse transcriptase Inhibitor Dapivirine Family 5 72
Amg 423 family 7 47
Class II cytokine receptor Ligand IL-10 Family 7 45
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... 5 0
Transient receptor potential cation channel subfamily V member... 3 2
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 4


External ID

Functional Category

Molecule Name

CFAMM00391033 CHEMBL185685 Bioactive (2R)-N-(4-tert-butylphenyl)-4-(6-chloro-4-methylpyridazin-3-yl)-2-methylpiperazine-1-carboxamide
CFAMM00391034 CHEMBL362548 Bioactive (2R)-N-(4-tert-butylphenyl)-2-methyl-4-(4-methylpyridazin-3-yl)piperazine-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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