CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM886
Family Name Melanocortin receptor 4 and Melanocortin receptor 3 ligand SureCN12533598 family
No. of Seeds 6 No. of Other Members 53
Family Centroid CFAMM00049611 Functional Category Bioactive
Superfamily Retinal dehydrogenase 1 and Melanocortin receptor 4 Binder Superfamily
Class Class 3243

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Haloperidol Family 5 53
Delta-type opioid receptor Ligand Loperamide Family 8 55
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
C-C chemokine receptor type 5 ligand benzyl N-[1-[[(3S,4R)-1-(... 2 4
C-C chemokine receptor type 5 ligand 1-[1-[[(3S,4R)-1-(cyclope... 7 13
C-C chemokine receptor type 5 ligand N-[1-[[(3S,4R)-1-(cyclope... 1 16
C-C chemokine receptor type 5 ligand N-[1-[[(3S,4R)-1-(cyclope... 5 1
Melanocortin receptor 4 ligand 2-[(1S)-6-chloro-1'-[(3S,4R)-4-... 2 12
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 10
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 10 20
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 13 0
C-C chemokine receptor type 5 ligand (2R)-3-cyclopropyl-2-[(3S... 6 0
Substance-P receptor ligand 1-[(3S,4R)-3-[(1R)-1-[3,5-bis(trif... 9 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 3
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 2 2
Cannabinoid receptor 2 ligand [(4S,4aR,8aS)-4-hydroxy-4-phenyl... 3 0
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00316888 CHEMBL1765248 Bioactive [(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpyrrolidin-3-yl)methanone
CFAMM00316835 CHEMBL1092571 Bioactive [(3R,4S)-1-cyclobutyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]-[(3R,5S)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl]methanone
CFAMM00316858 CHEMBL1092209 Bioactive SureCN12533636

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46270 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543