CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8867
Family Name Collagenase 3 and Matrilysin inhibitor N-({4'-[(1-BENZOFURAN-2-YLCARBONYL)AMINO]-1,1'-BIPHENYL-4-YL}SULFONYL)-L-VALINE family
No. of Seeds 24 No. of Other Members 45
Family Centroid CFAMM00365478 Functional Category Bioactive
Superfamily Collagenase 3 and Beta-lactamase Binder Superfamily 2
Class Class 1685

Cousin Family NamesSeedsMembers
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-3-[3-[(5... 1 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family 3 2
Collagenase 3 and 72 kDa type IV collagenase inhibitor SureCN3... 2 0
Macrophage metalloelastase and Collagenase 3 inhibitor SureCN4... 11 3
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Collagenase 3 and Neutrophil collagenase inhibitor SureCN36031... 12 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2S)-2-... 5 0
Growth hormone secretagogue receptor type 1 ligand N-[5-[(3R,5... 6 8
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 7 0
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 3 1
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 1 6
Macrophage metalloelastase and Collagenase 3 inhibitor (2S)-2-... 3 4
Macrophage metalloelastase and Collagenase 3 inhibitor SureCN4... 2 0
Neuropeptide Y receptor type 5 ligand 3-dibenzofuran-2-yl-1-[(... 1 2
Excitatory amino acid transporter 2 and Excitatory amino acid ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00391175 CHEMBL408720 Bioactive (2S)-2-[[4-[4-(1-benzofuran-2-ylmethylamino)phenyl]phenyl]sulfonylamino]-3-methylbutanoic acid
CFAMM00391142 CHEMBL541218 Bioactive SureCN3610137
CFAMM00391148 CHEMBL563896 Bioactive SureCN3616918
CFAMM00391161 CHEMBL365923 Bioactive SureCN3614771
CFAMM00391174 CHEMBL564998 Bioactive (2S)-2-[[4-[4-[(4-amino-3-methyl-1-benzofuran-2-carbonyl)amino]phenyl]phenyl]sulfonylamino]-3-methylbutanoic acid
CFAMM00391128 CHEMBL185933 Bioactive SureCN3607665
CFAMM00391180 CHEMBL188542 Bioactive SureCN3619909
CFAMM00391160 CHEMBL564232 Bioactive SureCN13314491
CFAMM00391133 CHEMBL564564 Bioactive SureCN3611937
CFAMM00391146 CHEMBL2337129 Bioactive AGN-PC-04TKJY
CFAMM00391159 CHEMBL187791 Bioactive SureCN3616420
CFAMM00391172 CHEMBL263750 Bioactive SureCN3612416
CFAMM00391171 CHEMBL552213 Bioactive SureCN8288279
CFAMM00391177 CHEMBL264067 Bioactive SureCN3618624
CFAMM00391144 CHEMBL559804 Bioactive SureCN13314451
CFAMM00391130 CHEMBL439668 Bioactive SureCN3617911
CFAMM00391143 CHEMBL362522 Bioactive SureCN3612325

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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