CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8872
Family Name Sodium-dependent serotonin transporter inhibitor SureCN6575591 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00391212 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Sodium-dependent serotonin transporter Binder Superfamily
Class Class 409

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
Melatonin receptor type 1A Ligand Melatonin Family 20 988
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
D(2) dopamine receptor Ligand SLV-314 Family 19 69
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 4
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 10
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 1
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-075G9A... 3 2
Sodium-dependent serotonin transporter and D(2) dopamine recep... 3 0
Serine/threonine-protein kinase B-raf inhibitor pyrrole-based ... 2 0
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 7
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 1 2
Sodium-dependent serotonin transporter inhibitor (2S)-1-[(2S,4... 7 1
Sigma non-opioid intracellular receptor 1 ligand 1'-[4-[1-(4-f... 2 0
Glucagon receptor ligand SureCN2647807 family 3 7
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Protein kinase C theta type and Protein kinase C delta type in... 10 7
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-04UHB... 4 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391212 CHEMBL186140 Bioactive SureCN6575591
CFAMM00391211 CHEMBL406134 Bioactive SureCN6574196

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26820 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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