CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8874
Family Name Metabotropic glutamate receptor 5 ligand SureCN4297614 family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00391241 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and Metabotropic glutamate receptor 5 Binder Superfamily
Class Class 1696

Cousin Family NamesSeedsMembers
Fibroblast growth factor receptor 3 Ligand BMS-582664 Family 2 23
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Oxytocin receptor and Vasopressin V1a receptor Ligand PF-32741... 4 36
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 31 11
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Metabotropic glutamate receptor 5 ligand SureCN4699900 family 1 5
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ITK/TS... 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 25 2
Vascular endothelial growth factor receptor 2 and Platelet-der... 16 11
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Vascular endothelial growth factor receptor 2 and Serine/threo... 6 13
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Oxytocin receptor ligand AGN-PC-07C71T family 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391243 CHEMBL426976 Bioactive SureCN4703375
CFAMM00391241 CHEMBL186151 Bioactive SureCN4297614

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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