CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8883
Family Name Coagulation factor X and Coagulation factor IX inhibitor pyrazole analog 3n family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00391355 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 840

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Coagulation factor X Inhibitor SN429 Family 23 100
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-09M6D1 family 2 5
Glucocorticoid receptor ligand N-ethyl-2-fluoro-N-[3,3,3-trifl... 16 7
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 11 0
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 6 1
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 3 0
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Serine/threonine-protein kinase PLK1 and MAP kinase-activated ... 1 2
Coagulation factor X inhibitor SureCN8169809 family 12 18
Coagulation factor X inhibitor SureCN8168539 family 3 0
Coagulation factor X inhibitor AGN-PC-0749JT family 1 0
Coagulation factor X inhibitor AGN-PC-0749DA family 3 2
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Coagulation factor X inhibitor DPC 423 derivative, 8 family 1 2
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Coagulation factor X inhibitor SureCN5254091 family 5 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R6UP family 2 0
P2X purinoceptor 7 inhibitor SureCN1194877 family 1 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391353 CHEMBL360197 Bioactive pyrazole analog 3o
CFAMM00391355 CHEMBL186272 Bioactive pyrazole analog 3n

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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