CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8907
Family Name D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-PC-00BL08 family
No. of Seeds 9 No. of Other Members 7
Family Centroid CFAMM00313397 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Prothrombin Binder Superfamily
Class Class 2613

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-612... 1 11
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... 4 3
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-5-[4-(oxan-4-... 21 7
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Type-1 angiotensin II receptor ligand AGN-PC-04X45B family 9 12
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OU family 6 6
Growth hormone secretagogue receptor type 1 ligand (E)-5-amino... 1 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 16
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino... 3 1
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 15 16
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-[4-... 1 1
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(2-... 5 1
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Melanin-concentrating hormone receptor 1 ligand N-methyl-4-(4-... 1 0
Histone deacetylase 6 inhibitor 2-[(E)-2-(4-fluorophenyl)-3-th... 1 1
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 1 0
Prothrombin and Coagulation factor X inhibitor [(1R)-5-amino-1... 2 3
Coagulation factor X inhibitor 5-chloro-N-[(1R,2S)-2-[[4-[1-(p... 2 0
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
Histone deacetylase 1 inhibitor AGN-PC-007IQK family 1 4
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butyl... 8 6
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Kappa-type opioid receptor ligand 2-[2-oxo-2-[(2S)-2-(pyrrolid... 2 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Calpain-1 catalytic subunit and Cathepsin B inhibitor N-(4-ami... 1 0
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-methylsul... 3 0
Carbonic anhydrase 2 inhibitor AGN-PC-07C00S family 4 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 13
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 3
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0
Peptide deformylase inhibitor N-[(2S)-1-[cyclopentylmethyl-[2-... 1 0
Lethal(3)malignant brain tumor-like protein 1 and Nuclear rece... 1 10
DNA-(apurinic or apyrimidinic site) lyase and Cytochrome P450 ... 1 1
Histone deacetylase 6 inhibitor AGN-PC-0C7PT7 family 4 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391585 CHEMBL187122 Bioactive AGN-PC-072QOY

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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