CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8914
Family Name Ribosomal protein S6 kinase alpha-5 inhibitor AGN-PC-075HAD family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00391603 Functional Category Bioactive
Superfamily Beta-lactamase and Ribosomal protein S6 kinase alpha-5 Binder Superfamily
Class Class 1333

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... 7 12
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Aromatase Inhibitor NSC-356781 Family 3 10
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 5 58
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
Ribosomal protein S6 kinase beta-1 and Rho-associated protein ... 2 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 9
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 6 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Smoothened homolog and Sonic hedgehog protein inhibitor N-cycl... 3 2
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 0
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
D(4) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 0
Cathepsin K inhibitor SureCN4141224 family 3 0
Nociceptin receptor and Potassium voltage-gated channel subfam... 5 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 12 3
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
Ribosomal protein S6 kinase beta-1 and Rho-associated protein ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391604 CHEMBL365832 Bioactive 607370-99-0
CFAMM00391603 CHEMBL187340 Bioactive AGN-PC-075HAD

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27746 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543