CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8915
Family Name Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-methoxyphenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00391607 Functional Category Bioactive
Superfamily Urotensin-2 receptor and Kappa-type opioid receptor Binder Superfamily
Class Class 511

Cousin Family NamesSeedsMembers
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Histamine H3 receptor Ligand A-349821 Family 49 228
Urotensin-2 receptor Ligand SB-328872 Family 5 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 14
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 2 3
Disintegrin and metalloproteinase domain-containing protein 17... 28 10
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 10
Mu-type opioid receptor ligand AGN-PC-075GCP family 2 8
Acetylcholinesterase inhibitor 3-(1-benzyl-1-methylpiperidin-1... 3 24
Histamine H3 receptor ligand SureCN5093846 family 2 3
Fatty-acid amide hydrolase 1 inhibitor [3-(3-carbamoyl-5-methy... 1 1
Sigma non-opioid intracellular receptor 1 ligand 1-benzyl-6'-(... 1 4
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 4
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[6-(4-c... 1 1
Melanin-concentrating hormone receptor 1 ligand N-methyl-N-[(3... 2 2
Melanin-concentrating hormone receptor 1 and Cytochrome P450 2... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391610 CHEMBL363238 Bioactive (3S)-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]-3-[methyl-[5-[4-(trifluoromethoxy)phenyl]thiophene-2-carbonyl]amino]pyrrolidine-1-carboxamide
CFAMM00391609 CHEMBL189756 Bioactive (3S)-3-[[5-(4-methoxy-2-methylphenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00391607 CHEMBL189650 Bioactive (3S)-3-[[5-(4-methoxyphenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00391612 CHEMBL187371 Bioactive (3S)-3-[[5-(2-chloro-4-ethoxyphenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26195 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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