CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8920
Family Name Progesterone receptor ligand AGN-PC-00B9AT family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00391643 Functional Category Bioactive
Superfamily Progesterone receptor and D(2) dopamine receptor Binder Superfamily 2
Class Class 667

Cousin Family NamesSeedsMembers
Toll-like receptor 7 Ligand Imiquimod Family 3 237
Histamine H1 receptor Ligand Mizolastine Family 14 603
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
HCV NS4B protein Inhibitor Clemizole Family 2 43
SB989 family 17 91
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 2 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Nociceptin receptor and Kappa-type opioid receptor ligand 1-[1... 4 4
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 5 2
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Progesterone receptor ligand 1-methyl-5-(3-pentan-3-yl-2-sulfa... 3 2
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 4 0
Nociceptin receptor and Mu-type opioid receptor ligand 2-(3-ch... 2 0
Pteridine reductase, putative inhibitor 1-[(3,4-dichlorophenyl... 2 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 3-(1-... 1 0
Progesterone receptor ligand 3-benzyl-5-(3-nitrophenyl)-1H-ben... 1 2


External ID

Functional Category

Molecule Name

CFAMM00391640 CHEMBL187488 Bioactive 3-(3-cyclopentyl-2-oxo-1H-benzimidazol-5-yl)-5-fluorobenzonitrile
CFAMM00391639 CHEMBL361901 Bioactive AGN-PC-006SYV
CFAMM00391644 CHEMBL188780 Bioactive AGN-PC-00DLCZ
CFAMM00391643 CHEMBL188131 Bioactive AGN-PC-00B9AT

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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