CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8922
Family Name Vascular endothelial growth factor receptor 2 ligand urea deriv. 22 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00391649 Functional Category Bioactive
Superfamily Alpha-2A adrenergic receptor and Melanin-concentrating hormone receptor 1 Ligand AR-129330 Superfamily
Class Class 1144

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase JAK2 Inhibitor TG101348 Family 2 4
AP26113 family 16 90
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
Tubulin beta chain Inhibitor ABT-751 Family 1 2
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Inositol monophosphatase 1 inhibitor CHEMBL1588383 family 1 6
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 9
Wee1-like protein kinase and ALK tyrosine kinase receptor liga... 1 9
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 6 13
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibi... 1 3
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 0
Glucokinase inhibitor AGN-PC-03ZE4O family 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391648 CHEMBL188025 Bioactive urea deriv. 24
CFAMM00391649 CHEMBL187609 Bioactive urea deriv. 22

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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