CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8923
Family Name Vascular endothelial growth factor receptor 2 ligand urea deriv. 35 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00391652 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 9 and Mitogen-activated protein kinase 8 Binder Superfamily
Class Class 4519

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
GDC-0349 family 44 77
Tyrosine-protein kinase BTK Inhibitor CC-292 Family 6 10
JAK Inhibitor Momelotinib Family 33 83
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 1 7
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 4
Histamine H4 receptor ligand 2-[[6-iodo-2-(4-methylpiperazin-1... 4 2
Neuropeptide Y receptor type 5 ligand SureCN8898853 family 2 3
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Vascular endothelial growth factor receptor 2 ligand urea deri... 3 9
Aurora kinase A and Aurora kinase B inhibitor 2-[[5-chloro-2-[... 3 7
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Serine/threonine-protein kinase SMG1 and Serine/threonine-prot... 10 0
Serine/threonine-protein kinase SMG1 and Cyclin-dependent kina... 3 1
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 4 5
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 5
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... 1 1
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... 4 0
Protein-tyrosine kinase 2-beta inhibitor 4-N-[(1R,2R)-2-(dimet... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391652 CHEMBL187627 Bioactive urea deriv. 35
CFAMM00391651 CHEMBL189862 Bioactive TCMDC-138736

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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