CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8927
Family Name Melanin-concentrating hormone receptor 1 ligand SureCN3845324 family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00391672 Functional Category Bioactive with Natural Product
Superfamily Melanin-concentrating hormone receptor 1 Binder Superfamily 2
Class Class 3520

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C8 inhib... 6 5
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 7 9
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 13 6
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Melanin-concentrating hormone receptor 1 ligand 1-[4-(3-cyanop... 4 9
Melanin-concentrating hormone receptor 1 ligand SureCN14265737... 2 0
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanin-concentrating hormone receptor 1 ligand N-[2-[4-(3-cya... 3 9
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanin-concentrating hormone receptor 1 ligand SureCN14265866... 11 2
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN13655018... 6 23
Melanin-concentrating hormone receptor 1 ligand SureCN13918038... 6 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00CYMY ... 1 0
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 4 0
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Melanin-concentrating hormone receptor 1 ligand 1-[4-chloro-3-... 1 1
Neuropeptide Y receptor type 5 ligand SureCN6214451 family 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 3
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
Melanin-concentrating hormone receptor 1 ligand N-[1-[3-(4-chl... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391672 CHEMBL364162 Bioactive SureCN3845324
CFAMM00391678 CHEMBL189611 Bioactive AGN-PC-009EQH
CFAMM00391677 CHEMBL361215 Bioactive 1-(3-chloro-4-fluorophenyl)-3-[2-[4-(3-cyanophenyl)phenyl]-4-(dimethylamino)butyl]urea
CFAMM00391675 CHEMBL364871 Bioactive 1-[4-(3-cyanophenyl)phenyl]-1-(1-cyclopentylpiperidin-4-yl)-3-(3,5-dichlorophenyl)urea
CFAMM00391674 CHEMBL187721 Bioactive AGN-PC-008RFE
CFAMM00391681 CHEMBL189147 Bioactive SureCN3839096
CFAMM00391673 CHEMBL384701 Bioactive 3-(3-chloro-4-fluorophenyl)-1-(7-cyano-1,2,3,4-tetrahydronaphthalen-2-yl)-1-[3-(4-methylpiperazin-1-yl)propyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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