CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8933
Family Name Mitogen-activated protein kinase 14 inhibitor SureCN3305171 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00391725 Functional Category Bioactive
Superfamily Mast/stem cell growth factor receptor Kit and Abelson tyrosine-protein kinase 2 Inhibitor Imatinib Superfamily
Class Class 144

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 5 129
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Serine/threonine-protein kinase mTOR Inhibitor AZD2014 Family 2 41
GDC-0349 family 44 77
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 37 10
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Tyrosine-protein kinase BTK Inhibitor CC-292 Family 6 10
JAK Inhibitor Momelotinib Family 33 83
XL-888 family 16 85
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 7 1
Coagulation factor X inhibitor AGN-PC-075AY8 family 28 21
Mitogen-activated protein kinase 1 and Cytochrome P450 3A4 inh... 1 0
Metabotropic glutamate receptor 2 ligand AGN-PC-09QJ9P family 2 7
Hepatocyte growth factor receptor and Insulin receptor ligand ... 4 15
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 0
Transient receptor potential cation channel subfamily V member... 2 1
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 7 1
Mitogen-activated protein kinase 14 inhibitor ethyl N-[4-[5-(m... 5 2
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 3 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 2 0
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 12 0
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... 5 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Serine/threonine-protein kinase mTOR inhibitor 2-[4-[4-[(3S)-3... 3 0
Casein kinase II subunit alpha inhibitor CHEMBL401945 family 12 1
Coagulation factor X inhibitor AGN-PC-078Y0S family 7 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Mitogen-activated protein kinase 14 inhibitor ethyl 4-[5-[(3-f... 2 0
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Transient receptor potential cation channel subfamily V member... 3 2
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Aurora kinase A and Aurora kinase B inhibitor N-[(3E)-3-[5-(mo... 3 2
Melanin-concentrating hormone receptor 1 and Alpha-2A adrenerg... 1 1
Muscarinic acetylcholine receptor M1 ligand N'-[1-ethyl-2-[(E,... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391725 CHEMBL187857 Bioactive SureCN3305171

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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