CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8941
Family Name Melatonin receptor type 1B and Melatonin receptor type 1A ligand AGN-PC-03OG7G family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00391385 Functional Category Bioactive
Superfamily Acetylcholinesterase Inhibitor Rivastigmine Superfamily
Class Class 120

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Acetylcholinesterase Inhibitor Rivastigmine Family 2 59
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
5-hydroxytryptamine receptor 2A Ligand Pimavanserin Family 4 23
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Histamine H3 receptor Ligand A-349821 Family 49 228
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Acetylcholinesterase and Cholinesterase Inhibitor Caproctamine... 7 17
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
5-hydroxytryptamine receptor 2A and D(1A) dopamine receptor Li... 8 33
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Fatty-acid amide hydrolase 1 Inhibitor 8-phenyloctylcarbamic A... 12 1
Acetylcholinesterase inhibitor [(3aR,8bS)-3,8b-dimethyl-1,2,3a... 1 27
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
Sigma non-opioid intracellular receptor 1 ligand 1-[4-(4-metho... 1 0
3-hydroxyacyl-CoA dehydrogenase type-2 and Retinal dehydrogena... 1 15
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Stromelysin-1 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 26 12
Growth hormone secretagogue receptor type 1 ligand tert-butyl ... 5 4
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Histamine H3 receptor ligand SureCN6071181 family 2 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 8
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Motilin receptor and Growth hormone secretagogue receptor type... 1 2
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-006SR... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391800 CHEMBL19123 Bioactive AGN-PC-03OG7E
CFAMM00391799 CHEMBL281345 Bioactive SureCN8651045
CFAMM00391797 CHEMBL280142 Bioactive N-ethyl-4-[(1R)-6-methoxy-2,3-dihydro-1H-inden-1-yl]piperazine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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