CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8945
Family Name Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(2-chlorophenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00391858 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 Binder Superfamily 4
Class Class 3814

Cousin Family NamesSeedsMembers
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 15 16
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-[4-... 1 1
Melanin-concentrating hormone receptor 1 ligand N-methyl-4-(4-... 1 0
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 1 0
Coagulation factor X inhibitor 5-chloro-N-[(1R,2S)-2-[[4-[1-(p... 2 0
Kappa-type opioid receptor ligand 2-[2-oxo-2-[(2S)-2-(pyrrolid... 2 1
Capsid scaffolding protein inhibitor AC1LAC4T family 1 0
DNA-(apurinic or apyrimidinic site) lyase and Cytochrome P450 ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391857 CHEMBL362790 Bioactive (3S)-3-[[5-(2,4-dichlorophenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00391856 CHEMBL366309 Bioactive (3S)-3-[[5-(2-chloro-4-methylphenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00391861 CHEMBL359580 Bioactive (3S)-3-[[5-(4-chlorophenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00391859 CHEMBL188330 Bioactive (3S)-3-[[5-(4-chloro-2-methylphenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00391858 CHEMBL365400 Bioactive (3S)-3-[[5-(2-chlorophenyl)thiophene-2-carbonyl]-methylamino]-N-methyl-N-[(3R)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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