CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8948
Family Name Melatonin receptor type 1B and Melatonin receptor type 1A ligand 2-methyl-N-[[(1R,2R)-2-(2-propyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]propanamide family
No. of Seeds 16 No. of Other Members 6
Family Centroid CFAMM00391877 Functional Category Bioactive with Natural Product
Superfamily Melatonin receptor type 1A and Melatonin receptor type 1B Binder Superfamily 5
Class Class 1929

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-[(2... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN8115658 f... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391876 CHEMBL18960 Bioactive N-[[(1R,2R)-2-(2-ethyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]acetamide
CFAMM00391869 CHEMBL19109 Bioactive 1-ethyl-3-[[(1R,2R)-2-(2-propyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]urea
CFAMM00391882 CHEMBL18846 Bioactive N-[[(1R,2R)-2-(2-propan-2-yl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]cyclopropanecarboxamide
CFAMM00391875 CHEMBL19441 Bioactive 2-methyl-N-[[(1R,2R)-2-(2-propan-2-yl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]propanamide
CFAMM00391881 CHEMBL19260 Bioactive 1-ethyl-3-[[(1R,2R)-2-(2-ethyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]urea
CFAMM00391867 CHEMBL276921 Bioactive N-[[(1R,2R)-2-(2-propyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]propanamide
CFAMM00391873 CHEMBL19211 Bioactive N-[[(1R,2R)-2-(2-propyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]butanamide
CFAMM00391886 CHEMBL431103 Bioactive N-[[(1R,2R)-2-(2-ethyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]-2-methylpropanamide
CFAMM00391879 CHEMBL18845 Bioactive 2-methyl-N-[[(1R,2R)-2-[2-(4-phenylbutyl)-2,3-dihydro-1,3-benzoxazol-7-yl]cyclopropyl]methyl]propanamide
CFAMM00391885 CHEMBL553105 Bioactive N-[[(1R,2R)-2-(2-propan-2-yl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]butanamide
CFAMM00391865 CHEMBL19026 Bioactive N-[[(1R,2R)-2-[2-(4-phenylbutyl)-2,3-dihydro-1,3-benzoxazol-7-yl]cyclopropyl]methyl]butanamide
CFAMM00391878 CHEMBL278922 Bioactive N-[[(1R,2R)-2-(2-propan-2-yl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]acetamide
CFAMM00391871 CHEMBL428692 Bioactive N-[[(1R,2R)-2-(2-propan-2-yl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]propanamide
CFAMM00391884 CHEMBL19128 Bioactive N-[[(1R,2R)-2-(2-propyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]acetamide
CFAMM00391877 CHEMBL19050 Bioactive 2-methyl-N-[[(1R,2R)-2-(2-propyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]propanamide
CFAMM00391870 CHEMBL279343 Bioactive N-[[(1R,2R)-2-(2-propyl-2,3-dihydro-1,3-benzoxazol-7-yl)cyclopropyl]methyl]cyclopropanecarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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