CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8951
Family Name Transporter and Sodium-dependent dopamine transporter inhibitor 2-[[(3R,4R)-4-(4-chlorophenyl)-1-methylpiperidin-3-yl]methylsulfanyl]-N-methylacetamide family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00391818 Functional Category Bioactive
Superfamily Translocator protein Inhibitor Chlormezanone Superfamily
Class Class 472

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Acetylcholinesterase Inhibitor Ambenonium Family 4 71
Neuromedin-K receptor Ligand Osanetant Family 38 192
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 23
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholi... 2 34
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 4 13
Sodium-dependent dopamine transporter and Transporter inhibito... 4 3
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 7 31
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 7 16
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Vasopressin V1a receptor ligand N-[(2R)-3-(4-chlorophenyl)-1-[... 6 0
Transporter and Sodium-dependent dopamine transporter inhibito... 3 42
Transporter and Sodium-dependent dopamine transporter inhibito... 2 0
Lysosomal Pro-X carboxypeptidase inhibitor (2S,3S)-2-[(2-amino... 3 3
Renin and Potassium voltage-gated channel subfamily H member 2... 1 0
Renin and Potassium voltage-gated channel subfamily H member 2... 3 2
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
C-C chemokine receptor type 1 ligand N-[(2R)-1-[(4S)-4-(4-chlo... 15 6
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 6 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 2 6
Sodium-dependent dopamine transporter and Transporter inhibito... 6 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor methyl ... 6 2
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
Dipeptidyl peptidase 4 inhibitor SureCN14523901 family 7 1
Prelamin-A/C inhibitor CHEMBL1353052 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391902 CHEMBL188557 Bioactive AGN-PC-0064HR

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48688 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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