CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8952
Family Name G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor pyrazolo[3,4-d]pyrimidin-4-one deriv. 19k family
No. of Seeds 5 No. of Other Members 10
Family Centroid CFAMM00391265 Functional Category Bioactive
Superfamily G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 Binder Superfamily 2
Class Class 4675

Cousin Family NamesSeedsMembers
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Metabotropic glutamate receptor 5 Ligand N-(1,3-diphenyl-1h-py... 6 37
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07C64P fa... 8 4
Mitogen-activated protein kinase 14 inhibitor AGN-PC-00CSYM fa... 2 15
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 5-(2-... 6 83
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 5 18
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 5-(2-... 12 1
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
Metabotropic glutamate receptor 5 ligand 5-(4-chlorophenyl)-1,... 3 1
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Non-receptor tyrosine-protein kinase TYK2 ligand SureCN1298914... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor AGN-... 1 1
Cannabinoid receptor 1 ligand AGN-PC-07RA6C family 21 2
Survival motor neuron protein and Beta-lactamase inhibitor CHE... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391915 CHEMBL436284 Bioactive pyrazolo[3,4-d]pyrimidin-4-one deriv. 19d
CFAMM00391909 CHEMBL433590 Bioactive pyrazolo[3,4-d]pyrimidin-4-one deriv. 24b

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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