CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8959
Family Name 5-hydroxytryptamine receptor 7 ligand 5-methyl-6-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-11-yl)cyclohexa-1,3-diene-1-carbonitrile family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00391945 Functional Category Bioactive
Superfamily calcium channel, Histamine H1 receptor, nuclear receptor binding piperazine derivative Flunarizine Cyclizine Meclizine Superfamily
Class Class 115

Cousin Family NamesSeedsMembers
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Extracellular calcium-sensing receptor ligand Cinacalcet Family 2 30
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Sigma non-opioid intracellular receptor 1 Ligand Dimemorfan Fa... 5 15
D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 8 32
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 1
Sigma non-opioid intracellular receptor 1 ligand CHEMBL101300 ... 2 1
5-hydroxytryptamine receptor 7 and Sodium-dependent serotonin ... 5 1
Histamine H3 receptor ligand SureCN1641166 family 3 0
Histamine H3 receptor ligand 4-[6-(2-pyrrolidin-3-ylethyl)naph... 1 1
5-hydroxytryptamine receptor 1A ligand SureCN8901985 family 1 0
Histamine H3 receptor ligand 2-benzyl-4-[4-(2-pyrrolidin-1-yle... 8 4
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 0
Histamine H3 receptor ligand SureCN1640926 family 3 3
Melanocortin receptor 4 ligand 1-[3-[2-(4-tert-butylphenyl)phe... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00391945 CHEMBL188855 Bioactive 5-methyl-6-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-11-yl)cyclohexa-1,3-diene-1-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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