CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM896
Family Name Histamine H1 receptor and Cytochrome P450 2D6 ligand 2-[3-[(1R)-1-(3-chloropyridin-2-yl)ethyl]-1-benzothiophen-2-yl]-N,N-dimethylethanamine family
No. of Seeds 1 No. of Other Members 10
Family Centroid CFAMM00316984 Functional Category Bioactive
Superfamily Platelet-derived growth factor receptor alpha and Platelet-derived growth factor receptor beta Ligand 6,7-dichloro-3-thiophen-3-yl-quinoline Superfamily
Class Class 2021

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
Platelet-derived growth factor receptor alpha and Platelet-der... 5 48
Cytochrome P450 3A4 Inhibitor 3-(3-methylthiophen-2-yl)pyridin... 5 27
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
Metabotropic glutamate receptor 5 Ligand 2-methyl-4-(pyridin-3... 10 35
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 12
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 14
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 4
Histamine H1 receptor and Cytochrome P450 2D6 ligand N-methyl-... 1 0
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 8 6
Aromatase inhibitor 2-(2-chloropyridin-4-yl)-4-pyridin-3-yl-1,... 1 1
Nociceptin receptor and Mu-type opioid receptor ligand (1S,5S)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00316984 CHEMBL1092494 Bioactive 2-[3-[(1R)-1-(3-chloropyridin-2-yl)ethyl]-1-benzothiophen-2-yl]-N,N-dimethylethanamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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