CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8991
Family Name Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N,5-dihydroxy-3,3-dimethyl-1-[4-(quinolin-4-ylmethoxy)phenyl]sulfonylpiperidine-2-carboxamide family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00388314 Functional Category Bioactive
Superfamily Collagenase 3 and Disintegrin Binder Superfamily
Class Class 4678

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-hydro... 3 25
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
Disintegrin and metalloproteinase domain-containing protein 17... 1 3
Collagenase 3 and A disintegrin and metalloproteinase with thr... 5 6
5-hydroxytryptamine receptor 6 ligand SureCN5253197 family 4 2
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 2 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 1 3
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 7 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00392133 CHEMBL436277 Bioactive (2R,3R)-N,3-dihydroxy-1-[4-(isoquinolin-8-ylmethoxy)phenyl]sulfonyl-3-methylpiperidine-2-carboxamide
CFAMM00392131 CHEMBL189975 Bioactive (2R,5R)-N,5-dihydroxy-1-[4-(isoquinolin-1-ylmethoxy)phenyl]sulfonyl-3,3-dimethylpiperidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27285 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543