CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8992
Family Name Plasmepsin-1 and Plasmepsin-2 inhibitor N-[(2S,3S)-5-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-[[4-(1,3-benzodioxol-5-yl)phenyl]methoxy]-3-hydroxy-5-oxopentan-2-yl]-2,4,6-trifluorobenzamide family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00392136 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 1704

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Caspase-1 and Caspase-8 inhibitor N-[(6S)-1-[2-[[(3S)-2-hydrox... 3 1
Plasmepsin-1 and Plasmepsin-2 inhibitor N-[(2S,3S)-5-[[(2S)-1-... 2 4
Beta-secretase 1 inhibitor 1-N-[(2S,3R)-1-(3,5-difluorophenyl)... 8 7
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00392136 CHEMBL189976 Bioactive N-[(2S,3S)-5-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-[[4-(1,3-benzodioxol-5-yl)phenyl]methoxy]-3-hydroxy-5-oxopentan-2-yl]-2,4,6-trifluorobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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