CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8993
Family Name Integrin alpha-V and Integrin beta-5 inhibitor SureCN2489170 family
No. of Seeds 8 No. of Other Members 0
Family Centroid CFAMM00392139 Functional Category Bioactive
Superfamily Tryptophan 5-hydroxylase 1 and Integrin beta-5 Binder Superfamily
Class Class 2020

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 4
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
Melatonin receptor type 1A ligand N-[2-(5-methoxy-2-phenyl-1H-... 1 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2491273 f... 11 10
Integrin beta-3 and Integrin alpha-V inhibitor (3S,7S)-7-hydro... 5 1
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 14 2
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 3 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6220269 f... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03OERH f... 1 0
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-3-N-(7... 2 2
TGF-beta receptor type-1 ligand SureCN373216 family 3 14
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 1


External ID

Functional Category

Molecule Name

CFAMM00392145 CHEMBL364483 Bioactive AGN-PC-075IRI
CFAMM00392137 CHEMBL189979 Bioactive AGN-PC-075IQD
CFAMM00392144 CHEMBL194001 Bioactive SureCN2488319
CFAMM00392143 CHEMBL371368 Bioactive SureCN2490009
CFAMM00392142 CHEMBL364064 Bioactive SureCN2492420
CFAMM00392140 CHEMBL192994 Bioactive SureCN2488651
CFAMM00392139 CHEMBL190128 Bioactive SureCN2489170
CFAMM00392138 CHEMBL364808 Bioactive AGN-PC-075IP0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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