CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8998
Family Name Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 ligand SureCN3245307 family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00218670 Functional Category Bioactive
Superfamily Bacterial outer membrane Inhibitor HKI-9924129 Superfamily
Class Class 1053

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
JAK Inhibitor Momelotinib Family 33 83
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Peptide deformylase, mitochondrial Inhibitor 5-chloryl-2,4,6-q... 2 6
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Adenosine receptor A1 Ligand N-(4,6-diphenylpyrimidin-2-yl)ben... 4 8
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 7 7
Tyrosine-protein kinase ABL1 and Mitogen-activated protein kin... 1 3
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 8 4
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 4
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Mitogen-activated protein kinase 14 inhibitor pyrimido-pyrimid... 15 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-0762YG family 2 2
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 7 2
Transient receptor potential cation channel subfamily V member... 3 2
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 0
Melanin-concentrating hormone receptor 1 ligand (E)-3-(4-chlor... 3 7
Melanin-concentrating hormone receptor 1 ligand (E)-3-(4-chlor... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00392172 CHEMBL447223 Bioactive AGN-PC-078XAL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43599 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543