CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Pol polyprotein inhibitor AC1LA3TO family
No. of Seeds 8 No. of Other Members 0
Family Centroid CFAMM00305888 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily
Class Class 2411

Cousin Family NamesSeedsMembers
Renin Inhibitor CP-80794 Family 16 112
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Pol polyprotein inhibitor 169168-45-0 family 7 11
Pol polyprotein inhibitor 169273-51-2 family 10 0
Pol polyprotein inhibitor benzyl N-[(2S,3R)-4-[(3aR,6S,7aS)-6-... 3 2
Pol polyprotein inhibitor Sulfone deriv. 31 family 15 4
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 16 1
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 3 3
Cathepsin E and Renin inhibitor (2S)-N-[2-[[(2S,3S,5S)-1-cyclo... 4 0
Renin inhibitor (1R,2R,3S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl... 5 0
Pol polyprotein inhibitor AC1LAH8S family 11 1
Pol polyprotein inhibitor TYB5 family 2 0
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-h... 2 0
Pol polyprotein inhibitor AC1LA3V9 family 2 1
Pol polyprotein inhibitor AC1LACBC family 2 0


External ID

Functional Category

Molecule Name

CFAMM00305886 CHEMBL98589 Bioactive 169168-42-7
CFAMM00305885 CHEMBL432784 Bioactive 159878-24-7
CFAMM00305884 CHEMBL316694 Bioactive LY326910
CFAMM00305883 CHEMBL418978 Bioactive 159878-29-2
CFAMM00305889 CHEMBL317160 Bioactive 169168-52-9
CFAMM00305882 CHEMBL99267 Bioactive AC1LA3UI
CFAMM00305888 CHEMBL100089 Bioactive AC1LA3TO
CFAMM00305887 CHEMBL49002 Bioactive TYA5

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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