CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9032
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2S,3S)-3-amino-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-oxo-4-(1,3-thiazolidin-3-yl)butanamide;2,2,2-trifluoroacetic acid family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00392409 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 Binder Superfamily 3
Class Class 1354

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Cathepsin K Inhibitor Odanacatib Family 33 84
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Neuromedin-K receptor Ligand Senktide Family 15 22
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
5-hydroxytryptamine receptor 6 ligand N-[[(1R)-6-(3-fluorophen... 8 0
Prolyl endopeptidase inhibitor SureCN194654 family 3 4
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
Substance-P receptor and Neuromedin-K receptor ligand (3R,4S)-... 2 2
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-2-[... 14 4
Coagulation factor X inhibitor (6S,8aS)-N-[(1-carbamimidoylpip... 6 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2S... 16 24
Dipeptidyl peptidase 4 inhibitor (3S)-4-[(3R)-3-amino-4-(2,4,5... 1 1
Dipeptidyl peptidase 4 inhibitor (2S,3S)-3-amino-2-[4-(4-fluor... 1 0
Lysine-specific histone demethylase 1A and Amine oxidase [flav... 2 1
Dipeptidyl peptidase 4 inhibitor SureCN2709139 family 5 7
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Dipeptidyl peptidase 4 inhibitor (2S,3S)-3-amino-4-[(3S)-3-flu... 1 5
Histamine H3 receptor ligand N-ethyl-3-fluoro-3-[3-fluoro-4-(p... 3 0
Prolyl endopeptidase inhibitor 1-[(4R)-4-(pyrrolidine-1-carbon... 11 0
Kappa-type opioid receptor ligand SureCN5629426 family 3 2
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[2-(3-methy... 1 0
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00392409 CHEMBL190863 Bioactive (2S,3S)-3-amino-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-oxo-4-(1,3-thiazolidin-3-yl)butanamide;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48716 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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