CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM904
Family Name Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 inhibitor AGN-PC-07ZYDP family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00317057 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Tyrosine-protein kinase JAK2 Binder Superfamily
Class Class 122

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Histamine H4 receptor ligand 2-[[6-iodo-2-(4-methylpiperazin-1... 4 2
Neuropeptide Y receptor type 5 ligand SureCN8898853 family 2 3
Vascular endothelial growth factor receptor 2 ligand urea deri... 3 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 5
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00317057 CHEMBL1092925 Bioactive AGN-PC-07ZYDP
CFAMM00317056 CHEMBL496091 Bioactive AGN-PC-04SQI7

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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