CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9045
Family Name Prostaglandin E2 receptor EP4 subtype ligand 4-[(1S)-1-[[2-(trifluoromethyl)-5,6-dihydrobenzo[b][1]benzoxepine-10-carbonyl]amino]ethyl]benzoic acid family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00392562 Functional Category Bioactive
Superfamily Microsomal triglyceride transfer protein large subunit Inhibitor SLX-4090 Superfamily
Class Class 1003

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor alpha Ligand Bezafi... 2 17
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
Cholesteryl ester transfer protein Inhibitor Anacetrapib Family 3 63
C-C chemokine receptor type 2 Ligand CCX915 Family 3 25
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 8 12
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 12 0
Growth hormone secretagogue receptor type 1 ligand 2-[(2S)-1-[... 2 0
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
Caspase-1 inhibitor (3S)-3-[2-[3-(naphthalene-1-carbonylamino)... 13 5
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 14 1
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00392561 CHEMBL1910023 Bioactive 4-[1-[[2-(trifluoromethyl)-5,6-dihydrobenzo[b][1]benzoxepine-10-carbonyl]amino]cyclopropyl]benzoic acid
CFAMM00392562 CHEMBL1910022 Bioactive 4-[(1S)-1-[[2-(trifluoromethyl)-5,6-dihydrobenzo[b][1]benzoxepine-10-carbonyl]amino]ethyl]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23964 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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