CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9057
Family Name Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibitor 1-[3-[4-(2,3-diethyl-1,4-dioxo-2,3,9-triazaspiro[4.5]decan-9-yl)piperidine-1-carbonyl]-1-benzothiophen-2-yl]-3-methylurea family
No. of Seeds 5 No. of Other Members 14
Family Centroid CFAMM00148416 Functional Category Bioactive
Superfamily Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 Binder Superfamily 2
Class Class 1000

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-09M88E f... 1 7
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 0
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN1564756 f... 1 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00392640 CHEMBL2059097 Bioactive 1-[3-[4-(1,3-dioxospiro[6,7,8,9-tetrahydro-5H-pyrazolo[1,2-a]diazepine-2,3'-piperidine]-1'-yl)piperidine-1-carbonyl]-1-benzothiophen-2-yl]-3-methylurea
CFAMM00392639 CHEMBL2059098 Bioactive 1-[3-[4-(1,3-dioxospiro[6,7,8,9-tetrahydro-5H-pyrazolo[1,2-a]diazepine-2,3'-piperidine]-1'-yl)piperidine-1-carbonyl]-1-benzothiophen-2-yl]-3-ethylurea
CFAMM00392638 CHEMBL2059099 Bioactive 1-[3-[4-(1,3-dioxospiro[5,6,7,8,9,10-hexahydropyrazolo[1,2-a]diazocine-2,3'-piperidine]-1'-yl)piperidine-1-carbonyl]-1-benzothiophen-2-yl]-3-ethylurea
CFAMM00392631 CHEMBL1910404 Bioactive 1-[3-[4-[(5S)-3,3-dimethyl-1-oxo-2-oxa-9-azaspiro[4.5]decan-9-yl]piperidine-1-carbonyl]-1-benzothiophen-2-yl]-3-ethylurea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44649 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543