CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9060
Family Name Collagenase 3 and A disintegrin and metalloproteinase with thrombospondin motifs 4 inhibitor (2R)-3-methyl-2-[[4-[4-[(2-methylpyridin-4-yl)methoxy]phenyl]phenyl]sulfonylamino]butanoic acid family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00392731 Functional Category Bioactive
Superfamily Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Superfamily
Class Class 1002

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Apricoxib family 8 77
Indeglitazar family 3 39
Integrin beta-3 Inhibitor L-756568 Family 8 59
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 1 0
Cysteinyl leukotriene receptor 1 ligand 4-[(2S)-2-[[7-(quinoli... 6 15
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 1 3
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 8 3
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
Disintegrin and metalloproteinase domain-containing protein 17... 1 3
Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N... 4 1
Macrophage metalloelastase inhibitor (2S)-3-methyl-2-[[8-[3-(t... 2 6
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 3
Collagenase 3 and Neutrophil collagenase inhibitor 2-[1-(2-met... 2 0
Neuropeptide Y receptor type 5 ligand AGN-PC-040NYD family 3 7
Renin inhibitor SureCN6044003 family 1 1
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 2 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 13
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 2
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Menin and Histone-lysine N-methyltransferase 2A inhibitor 3-{4... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
Thromboxane-A synthase inhibitor AGN-PC-00FAD1 family 2 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00392731 CHEMBL1910466 Bioactive (2R)-3-methyl-2-[[4-[4-[(2-methylpyridin-4-yl)methoxy]phenyl]phenyl]sulfonylamino]butanoic acid
CFAMM00392730 CHEMBL1910467 Bioactive (2R)-3-methyl-2-[[4-[4-[[2-(trifluoromethyl)pyridin-4-yl]methoxy]phenyl]phenyl]sulfonylamino]butanoic acid
CFAMM00392732 CHEMBL1910465 Bioactive (2R)-3-methyl-2-[[4-[4-(pyridin-4-ylmethoxy)phenyl]phenyl]sulfonylamino]butanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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