CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9064
Family Name Muscarinic acetylcholine receptor M3 and Muscarinic acetylcholine receptor M2 ligand 5-methyl-5-[(3S)-3-phenoxypyrrolidin-1-yl]-2,2-diphenylhexanamide family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00392740 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M3 and Muscarinic acetylcholine receptor M1 Binder Superfamily
Class Class 4694

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M3 Ligand Darifenacin Family 3 17
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand A-349821 Family 49 228
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 9 0
Muscarinic acetylcholine receptor M3 ligand 5-[3-[(3-hydroxyph... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
C-C chemokine receptor type 1 ligand SureCN8184421 family 11 10
Histamine H3 receptor and D(3) dopamine receptor ligand AGN-PC... 1 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN4877195 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00392745 CHEMBL1910848 Bioactive 5-methyl-5-(3-phenoxyazetidin-1-yl)-2,2-diphenylhexanamide
CFAMM00392744 CHEMBL1910849 Bioactive 5-methyl-5-(4-phenoxypiperidin-1-yl)-2,2-diphenylhexanamide
CFAMM00392742 CHEMBL1910853 Bioactive 5-[(3S)-3-(4-hydroxyphenoxy)pyrrolidin-1-yl]-5-methyl-2,2-diphenylhexanamide
CFAMM00392741 CHEMBL1910852 Bioactive 5-[(3S)-3-(2-hydroxyphenoxy)pyrrolidin-1-yl]-5-methyl-2,2-diphenylhexanamide
CFAMM00392740 CHEMBL1910846 Bioactive 5-methyl-5-[(3S)-3-phenoxypyrrolidin-1-yl]-2,2-diphenylhexanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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