CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9069
Family Name Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell growth factor receptor Kit ligand 4-[3-(4-piperazin-1-ylphenyl)-1,2-dihydropyrazolo[3,4-b]pyridin-6-ylidene]cyclohexa-2,5-dien-1-one family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00192402 Functional Category Bioactive
Superfamily Prelamin-A/C and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 3178

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Tyrosine kinase Inhibitor PKI166 Family 17 198
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-072YMN ... 7 11
Serine/threonine-protein kinase B-raf inhibitor SureCN1013580 ... 2 0
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Proto-oncogene tyrosine-protein kinase Src and Cyclin-dependen... 2 1
Epidermal growth factor receptor and Tyrosine-protein kinase A... 4 3
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 3 6
Adenosine receptor A3 and Adenosine receptor A2a ligand 4-(5-b... 2 5
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 5
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... 2 13
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Vascular endothelial growth factor receptor 2 and Vascular end... 4 2
Lysine--tRNA ligase inhibitor 4-[[[2-(2-piperazin-1-ylpyridin-... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 7 6
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 1
Adenosine receptor A2a ligand AGN-PC-077RYF family 3 0
Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... 2 4
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-07CQG5 ... 2 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-04WWHE family 2 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-04WVYY family 1 0
Serine/threonine-protein kinase Chk2 inhibitor (6E)-4-fluoro-6... 3 6


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44864 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543