CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM907
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor 4-[[5-[[4-(benzenesulfonyl)-3-methylanilino]methyl]-2-methylimidazol-1-yl]methyl]benzonitrile family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00317065 Functional Category Bioactive
Superfamily Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor 4-[[5-[[4-(benzenesulfonyl)-3-methylanilino]methyl]-2-methylimidazol-1-yl]methyl]benzonitrile Superfamily
Class Class 1989

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Protein farnesyltransferase subunit beta Inhibitor BMS-316810 ... 11 18
Farnesyltransferase beta subunit, putative and Protein farnesy... 12 4
Motilin receptor and Growth hormone secretagogue receptor type... 2 2
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 1 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Protein farnesyltransferase alpha subunit and Protein farnesyl... 5 0
Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... 6 2
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 4 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor AG... 3 1
Cannabinoid receptor 2 ligand 4-[[2-tert-butyl-1-(cyclohexylme... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00317069 CHEMBL109303 Bioactive AGN-PC-074XY1
CFAMM00317068 CHEMBL112940 Bioactive 4-[[5-[[4-(benzenesulfonyl)anilino]methyl]imidazol-1-yl]methyl]benzonitrile
CFAMM00317065 CHEMBL114086 Bioactive 4-[[5-[[4-(benzenesulfonyl)-3-methylanilino]methyl]-2-methylimidazol-1-yl]methyl]benzonitrile
CFAMM00317064 CHEMBL112324 Bioactive AGN-PC-074Y2D

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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