CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9085
Family Name C-C chemokine receptor type 5 ligand SureCN13543564 family
No. of Seeds 10 No. of Other Members 3
Family Centroid CFAMM00392862 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 and Type-1 angiotensin II receptor Binder Superfamily
Class Class 2341

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Histamine H1 receptor Ligand Mizolastine Family 14 603
Integrin alpha-4 Inhibitor CDP323 Family 8 17
BIBT986 family 7 96
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Type-2 angiotensin II receptor Ligand PD-123319 Family 3 39
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
C-C chemokine receptor type 5 ligand AC1LA88C family 2 9
Bombesin receptor subtype-3 ligand SureCN3515839 family 1 0
Survival motor neuron protein and Menin inhibitor CHEMBL132797... 1 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
C-C chemokine receptor type 5 ligand AC1LA25C family 3 6
C-C chemokine receptor type 5 ligand (2R)-3-cyclobutyl-2-[(3S,... 9 4
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 3-(6-amin... 5 10
Prostaglandin D2 receptor 2 ligand SureCN2215286 family 7 5
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 5 2
Microsomal triglyceride transfer protein large subunit inhibit... 7 4
A disintegrin and metalloproteinase with thrombospondin motifs... 1 3
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
C-C chemokine receptor type 5 ligand [4-[2-[3-(2-ethylbenzimid... 5 12
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Histamine H3 receptor ligand SureCN2878688 family 8 1
Histamine H1 receptor and Histamine H4 receptor ligand [4-[2-[... 1 1
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0
C-C chemokine receptor type 5 ligand (2R)-2-[(3S,4S)-3-[[4-(2-... 5 0
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
C-C chemokine receptor type 5 ligand (2R)-3-cyclobutyl-2-[(3S,... 2 0
Type-1 angiotensin II receptor and Type-1A angiotensin II rece... 3 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00IW9E f... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Type-2 angiotensin II receptor and Type-1A angiotensin II rece... 2 24
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
C-C chemokine receptor type 5 ligand SureCN13543570 family 2 0
C-C chemokine receptor type 5 ligand 1-[4-(3-chlorophenyl)-4-[... 3 1
Integrin alpha-4 inhibitor (2S)-2-[(2-bromo-3-oxospiro[3.5]non... 9 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00392871 CHEMBL193972 Bioactive (2R)-2-[(3S,4S)-3-[[4-[2-(benzimidazol-1-yl)ethyl]piperidin-1-yl]methyl]-4-phenylpyrrolidin-1-yl]-2-cyclohexylacetic acid
CFAMM00392864 CHEMBL442619 Bioactive SureCN13543571
CFAMM00392870 CHEMBL191139 Bioactive (2R)-2-[(3S,4S)-3-[[4-(benzimidazol-1-ylmethyl)piperidin-1-yl]methyl]-4-phenylpyrrolidin-1-yl]-2-cyclohexylacetic acid
CFAMM00392863 CHEMBL444497 Bioactive SureCN13543569
CFAMM00392869 CHEMBL505443 Bioactive SureCN3525724
CFAMM00392862 CHEMBL443936 Bioactive SureCN13543564
CFAMM00392868 CHEMBL508114 Bioactive SureCN13543572
CFAMM00392874 CHEMBL193440 Bioactive SureCN7987164
CFAMM00392867 CHEMBL364070 Bioactive SureCN7931862
CFAMM00392873 CHEMBL506273 Bioactive SureCN13543565

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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