CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9086
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[9-(4-fluorophenyl)-9-bicyclo[3.3.1]nonanyl]acetic acid family
No. of Seeds 2 No. of Other Members 15
Family Centroid CFAMM00392888 Functional Category Bioactive
Superfamily Cyclooxygenase Inhibitor Flurbiprofen Superfamily
Class Class 368

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
CPI-613 family 4 35
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
Macrophage migration inhibitory factor Inhibitor 3,3,3-tris(4-... 4 16
Glutamate carboxypeptidase 2 Inhibitor 2-(3-cyanobenzyl)-5-mer... 1 0
Calcium-activated potassium channel subunit alpha-1 Ligand Tri... 1 10
Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-c... 4 43
Free fatty acid receptor 1 and Free fatty acid receptor 4 liga... 1 7
Aldo-keto reductase family 1 member C3 inhibitor (8R,9S,13S,14... 2 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 4
Peroxisome proliferator-activated receptor gamma ligand SureCN... 3 3
Metabotropic glutamate receptor 1 ligand SureCN186260 family 1 4
Sodium-dependent dopamine transporter inhibitor AGN-PC-074TA8 ... 2 5
7a-hydroxy-7-phenyl-3,3a,4,5,6,7-hexahydro-1-benzofuran-2-one ... 4 0


External ID

Functional Category

Molecule Name

CFAMM00392888 CHEMBL1911395 Bioactive 2-[9-(4-fluorophenyl)-9-bicyclo[3.3.1]nonanyl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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