CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9102
Family Name NS5B protein inhibitor AC1NQMYP family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00393006 Functional Category Bioactive
Superfamily NS5B protein and Retinoic acid receptor alpha Binder Superfamily
Class Class 3380

Cousin Family NamesSeedsMembers
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
SF1 family 1 10
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Prostaglandin E synthase Inhibitor L-655240 Family 3 46
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Cytosolic phospholipase A2 Inhibitor WAY-196025 Family 4 13
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 1 1
NS5B protein inhibitor AC1NQMYG family 6 12
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4R,... 3 7
Cysteinyl leukotriene receptor 1 ligand (2S)-3-[(1S)-3-(2-acet... 6 1
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 6
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Glutamate receptor ionotropic, NMDA 1 ligand (3S)-3-[2-[4-(ami... 2 2
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 4
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 20 37
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 5 2
Prostaglandin E2 receptor EP4 subtype ligand SureCN3567929 family 10 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
Prostaglandin D2 receptor 2 ligand SureCN2189431 family 7 1
NS5B protein inhibitor AC1O5AET family 3 1
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Substance-P receptor ligand SureCN7796965 family 9 1
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0
Substance-P receptor ligand SureCN7790374 family 6 0
5-hydroxytryptamine receptor 4 ligand 4-[2-[4-[[(1-propan-2-yl... 1 1
Proline--tRNA ligase, cytoplasmic and Bifunctional glutamate/p... 1 6
Gonadotropin-releasing hormone receptor ligand 4-[2-[[(2S)-2-[... 1 0
Cysteinyl leukotriene receptor 1 ligand 3-[5-[[3-[(E)-2-(7-chl... 4 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Capsid scaffolding protein inhibitor 4-[[[5-[(E)-2-(7-chloroqu... 1 1
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
C-C chemokine receptor type 2 ligand AGN-PC-03NT5I family 5 18
Glutamate receptor 4 and Glutamate receptor 2 ligand SureCN437... 4 12


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393009 CHEMBL362909 Bioactive AC1O5AEZ
CFAMM00393008 CHEMBL191196 Bioactive AC1O5ABV
CFAMM00393007 CHEMBL363199 Bioactive AC1O5ABM
CFAMM00393006 CHEMBL361232 Bioactive AC1NQMYP
CFAMM00393005 CHEMBL362834 Bioactive AC1NQMYM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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