CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9104
Family Name Neuropeptide Y receptor type 5 ligand 2-fluoro-N-[5-[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]pentyl]benzenesulfonamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00393019 Functional Category Bioactive
Superfamily Cyclin-T1 and Cannabinoid receptor 2 Binder Superfamily
Class Class 1257

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Serine/threonine-protein kinase B-raf Inhibitor GSK2118436 Family 5 19
Cyclin-dependent kinase 2 Inhibitor 4-(2,4-dimethyl-thiazol-5-... 2 14
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
C-C chemokine receptor type 4 Ligand N-(4-tert-butylthiazol-2-... 3 9
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-ethy... 2 2
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Histamine H3 receptor Ligand 2-(1,4'-bipiperidin-1'-yl)thiazol... 2 23
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Neuropeptide Y receptor type 5 and Potassium voltage-gated cha... 2 0
Amine oxidase [flavin-containing] B inhibitor 4-(4-fluoropheny... 3 4
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Neuropeptide Y receptor type 5 ligand N-[5-[(4-thiophen-3-yl-1... 1 4
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
G1/S-specific cyclin-E1 and G1/S-specific cyclin-E2 inhibitor ... 5 1
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor CDK Inhibito... 8 3
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Methionine aminopeptidase 2 inhibitor SureCN5376630 family 1 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
Mitogen-activated protein kinase 14 inhibitor 303163-37-3 family 1 2
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
Transient receptor potential cation channel subfamily V member... 1 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393019 CHEMBL1912081 Bioactive 2-fluoro-N-[5-[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]pentyl]benzenesulfonamide
CFAMM00393017 CHEMBL1912087 Bioactive 2,4-dimethyl-N-[5-[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]pentyl]-1,3-thiazole-5-sulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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