CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9109
Family Name Dipeptidyl peptidase 4 inhibitor (2S,3S)-3-amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutanoic acid;2,2,2-trifluoroacetic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00393030 Functional Category Bioactive
Superfamily Neprilysin and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 260

Cousin Family NamesSeedsMembers
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Delta-type opioid receptor Ligand H-cxp-ala-gly-phe-leu-oh Family 1 8
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
Substance-P receptor and Neuromedin-K receptor ligand (3R,4S)-... 2 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 1 1
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Dipeptidyl peptidase 4 inhibitor (2S,3S)-3-amino-4-[(3S)-3-flu... 1 5
Dipeptidyl peptidase 4 inhibitor 3-[2-[(4R,5R)-5-amino-2-oxo-4... 1 4
Kappa-type opioid receptor ligand SureCN5629426 family 3 2
Neutrophil elastase inhibitor 4-[(E)-3-[[(2S)-3-methyl-1-oxo-1... 2 6
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0
Neutrophil elastase inhibitor 3-[[(2S)-3-methyl-1-oxo-1-[2-[(1... 1 0
Dipeptidyl peptidase 4 inhibitor 5-[4-[(2S,3S)-3-amino-4-[(3S)... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393030 CHEMBL191327 Bioactive (2S,3S)-3-amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutanoic acid;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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