CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9118
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor N-(2-chloro-5-quinazolin-6-ylpyridin-3-yl)-4-fluorobenzenesulfonamide family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00393112 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Tyrosine-protein kinase JAK2 Binder Superfamily
Class Class 122

Cousin Family NamesSeedsMembers
Neuropeptide Y receptor type 5 Ligand CGP71683A Family 5 74
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
Plasminogen and Urokinase-type plasminogen activator Inhibitor... 3 26
NF-kappa-B Inhibitor 9-chloro-5h-6-thia-4,5-diaza-chrysene 6,6... 3 27
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 1 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 0
Histamine H4 receptor ligand 2-[[6-iodo-2-(4-methylpiperazin-1... 4 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 15 3
Aurora kinase A and Aurora kinase B inhibitor 2-[[5-chloro-2-[... 3 7
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0760... 4 0
Serine/threonine-protein kinase SMG1 and Serine/threonine-prot... 10 0
Serine/threonine-protein kinase SMG1 and Cyclin-dependent kina... 3 1
Bombesin receptor subtype-3 and Nuclear receptor subfamily 1 g... 3 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... 5 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor AG... 1 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 4 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1
Histamine H4 receptor ligand 2-[[6-chloro-2-(4-methylpiperazin... 7 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393112 CHEMBL1914716 Bioactive N-(2-chloro-5-quinazolin-6-ylpyridin-3-yl)-4-fluorobenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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