CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9120
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-[3-(tetrazol-1-yl)phenyl]phenyl]butanamide;2,2,2-trifluoroacetic acid family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00393148 Functional Category Bioactive
Superfamily Prothrombin and Beta-lactamase Binder Superfamily 2
Class Class 3077

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Prothrombin inhibitor SureCN5855286 family 15 8
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 2
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 5 1
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Prothrombin inhibitor AGN-PC-09QLAK family 10 2
Calcitonin gene-related peptide type 1 receptor ligand SureCN2... 2 1
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Renin inhibitor AGN-PC-073MLF family 7 6
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (1... 4 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (3... 2 0
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (3... 1 1
Potassium voltage-gated channel subfamily H member 2 and ATP-s... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393143 CHEMBL2010845 Bioactive N-[(3S,4R)-3-fluoro-1-[[4-(trifluoromethyl)phenyl]methyl]piperidin-4-yl]-N-methyl-2-[4-(tetrazol-1-yl)phenyl]acetamide
CFAMM00393148 CHEMBL191473 Bioactive (2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-[3-(tetrazol-1-yl)phenyl]phenyl]butanamide;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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