CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9123
Family Name Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazole-3-carboxylate family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00393171 Functional Category Bioactive with Natural Product
Superfamily Scavenger receptor class B member 1 Binder Superfamily
Class Class 3548

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Dabigatran Family 7 182
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
JAK Inhibitor Momelotinib Family 33 83
XL-888 family 16 85
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1... 3 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-amin... 10 48
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 11
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 12
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9RSG ... 6 5
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
MAP kinase-activated protein kinase 2 inhibitor N-[4-(4-oxospi... 3 0
Neuropeptide Y receptor type 5 ligand AGN-PC-07R6YQ family 7 7
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Growth hormone secretagogue receptor type 1 ligand SureCN62436... 8 6
Scavenger receptor class B member 1 ligand 5-[9-[3-(3,5-difluo... 4 2
Scavenger receptor class B member 1 ligand 5-[9-[3-(4,6-dimeth... 7 3
5-hydroxytryptamine receptor 1D ligand N-[4-[[5-[3-[2-(dimethy... 4 16
Scavenger receptor class B member 1 ligand 2-[9-[3-(4,6-dimeth... 1 0
Scavenger receptor class B member 1 ligand 5-[9-[3-(6-fluoro-1... 1 4
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 5
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 8
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 8 13
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Histamine H3 receptor ligand AGN-PC-075YVW family 1 2
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... 2 6
Adenosine receptor A2b and Adenosine receptor A1 ligand [4-(2,... 6 15
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 1 2
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Vascular endothelial growth factor receptor 2 and Vascular end... 1 0
Neutrophil elastase inhibitor AGN-PC-076VCN family 3 25
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 0
Histamine H3 receptor ligand SureCN7961030 family 1 2
Methionine aminopeptidase 1 inhibitor ethyl 4-[4-(2-pyridin-2-... 2 3
Vascular endothelial growth factor receptor 1 and Vascular end... 1 0
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 2
Corticotropin-releasing factor receptor 1 ligand AGN-PC-006EKH... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393171 CHEMBL1914885 Bioactive methyl 9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazole-3-carboxylate
CFAMM00393164 CHEMBL2413516 Bioactive methyl 3-[[9-(4,6-dimethylpyrimidin-2-yl)-1-oxo-2,9-diazaspiro[5.5]undecan-2-yl]methyl]-1H-indole-5-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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